STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
M2T129_COCSN4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (413 aa)    
Predicted Functional Partners:
PAD1
Flavin prenyltransferase PAD1, mitochondrial; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family.
    
 0.963
M2TD40_COCSN
Uncharacterized protein.
  
  
 
0.912
M2TBY1_COCSN
Uncharacterized protein; Belongs to the FPP/GGPP synthase family.
  
 
 0.896
M2T528_COCSN
Uncharacterized protein.
 
    
 0.735
M2RTK5_COCSN
Nudix hydrolase domain-containing protein.
  
 
 0.656
M2SJD7_COCSN
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
    
 0.646
FDC1
Ferulic acid decarboxylase 1; Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4- vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites; Belongs to the UbiD family. UbiD-like/FDC subfamily.
    
 0.646
COQ6
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
  
  
 0.627
M2TA66_COCSN
Uncharacterized protein.
    
 0.606
M2QXU6_COCSN
4-hydroxyphenylpyruvate dioxygenase.
     
 0.596
Your Current Organism:
Bipolaris sorokiniana
NCBI taxonomy Id: 665912
Other names: B. sorokiniana ND90Pr, Bipolaris sorokiniana ND90Pr, Cochliobolus sativus ND90Pr
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