STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
M2T4Q5_COCSNERCC4 domain-containing protein. (949 aa)    
Predicted Functional Partners:
M2S2L2_COCSN
Uncharacterized protein.
   
 0.999
M2R424_COCSN
3'-5' exonuclease domain-containing protein.
    
 0.988
M2TBA7_COCSN
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.979
M2RMA0_COCSN
XPA_C domain-containing protein.
    
 0.977
M2SWA2_COCSN
AA_TRNA_LIGASE_II domain-containing protein.
  
 0.965
M2RQG5_COCSN
DUF1767 domain-containing protein.
    
 0.963
M2SML7_COCSN
Uncharacterized protein.
   
 0.924
M2SDK9_COCSN
Uncharacterized protein.
   
 0.913
M2SU74_COCSN
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
    
 0.900
M2T257_COCSN
MPN domain-containing protein.
   
 0.900
Your Current Organism:
Bipolaris sorokiniana
NCBI taxonomy Id: 665912
Other names: B. sorokiniana ND90Pr, Bipolaris sorokiniana ND90Pr, Cochliobolus sativus ND90Pr
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.