cobB protein (Acidilobus saccharovorans) - STRING interaction network

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cobB

NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily. (264 aa)

Predicted Functional Partners:

ASAC_0188

0.954

ASAC_0280

0.954

nadE

0.934

nadK

0.930

ASAC_1304

0.848

ASAC_0852

0.812

ASAC_0551

0.808

ASAC_0093

0.773

ASAC_0817

0.772

prs

0.703

Your Current Organism:

Acidilobus saccharovorans

NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASAC_0093	cobB	ASAC_0093	ASAC_0092	Hypothetical protein.	NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.	0.773
ASAC_0188	ASAC_0280	ASAC_0188	ASAC_0280	Nicotinamide-nucleotide adenylyltransferase.	Nicotinamide-nucleotide adenylyltransferase.	0.908
ASAC_0188	cobB	ASAC_0188	ASAC_0092	Nicotinamide-nucleotide adenylyltransferase.	NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.	0.954
ASAC_0188	nadE	ASAC_0188	ASAC_0274	Nicotinamide-nucleotide adenylyltransferase.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.930
ASAC_0188	nadK	ASAC_0188	ASAC_0398	Nicotinamide-nucleotide adenylyltransferase.	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.924
ASAC_0280	ASAC_0188	ASAC_0280	ASAC_0188	Nicotinamide-nucleotide adenylyltransferase.	Nicotinamide-nucleotide adenylyltransferase.	0.908
ASAC_0280	cobB	ASAC_0280	ASAC_0092	Nicotinamide-nucleotide adenylyltransferase.	NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.	0.954
ASAC_0280	nadE	ASAC_0280	ASAC_0274	Nicotinamide-nucleotide adenylyltransferase.	NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.	0.930
ASAC_0280	nadK	ASAC_0280	ASAC_0398	Nicotinamide-nucleotide adenylyltransferase.	Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.924
ASAC_0551	cobB	ASAC_0551	ASAC_0092	ATP-dependent helicase.	NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.	0.808
ASAC_0817	ASAC_0852	ASAC_0817	ASAC_0852	Isocitrate dehydrogenase (NADP+-dependent).	Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).	0.694
ASAC_0817	ASAC_1304	ASAC_0817	ASAC_1304	Isocitrate dehydrogenase (NADP+-dependent).	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.957
ASAC_0817	cobB	ASAC_0817	ASAC_0092	Isocitrate dehydrogenase (NADP+-dependent).	NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.	0.772
ASAC_0817	prs	ASAC_0817	ASAC_1066	Isocitrate dehydrogenase (NADP+-dependent).	Phosphoribosyl pyrophosphate synthase (PRPP synthase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).	0.607
ASAC_0852	ASAC_0817	ASAC_0852	ASAC_0817	Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).	Isocitrate dehydrogenase (NADP+-dependent).	0.694
ASAC_0852	ASAC_1304	ASAC_0852	ASAC_1304	Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.767
ASAC_0852	cobB	ASAC_0852	ASAC_0092	Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).	NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.	0.812
ASAC_0852	prs	ASAC_0852	ASAC_1066	Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).	Phosphoribosyl pyrophosphate synthase (PRPP synthase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).	0.970
ASAC_1304	ASAC_0817	ASAC_1304	ASAC_0817	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Isocitrate dehydrogenase (NADP+-dependent).	0.957
ASAC_1304	ASAC_0852	ASAC_1304	ASAC_0852	Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).	0.767

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