Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobDProbable cobalamin biosynthesis protein cobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (313 aa)    
Predicted Functional Partners:
ASAC_0144
Threonine-phosphate decarboxylase.
  
 0.998
ASAC_0143
Hypothetical protein.
    
  0.989
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
   
 0.980
ASAC_0141
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Belongs to the UPF0284 family.
 
  
 0.956
ASAC_0779
ATP:cobalamin adenosyltransferase.
    
 0.932
ASAC_0142
Adenosylcobinamide amidohydrolase, putative.
 
   
 0.930
ASAC_0147
Putative asparagine synthetase.
  
    0.874
ASAC_0140
Translation initiation factor Sui1; Belongs to the SUI1 family.
       0.653
ASAC_1202
Uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.613
ASAC_0139
Hypothetical protein.
       0.477
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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