| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASAC_0290 | pan | ASAC_0290 | ASAC_0295 | Putative HTH-type transcriptional regulator. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.767 |
| ASAC_0290 | rpl40e | ASAC_0290 | ASAC_1109 | Putative HTH-type transcriptional regulator. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.856 |
| ASAC_0705 | ASAC_0836 | ASAC_0705 | ASAC_0836 | ABC transporter, ATP binding protein. | Predicted metalloprotease, containing Jab1/MPN domain. | 0.653 |
| ASAC_0705 | ASAC_0953 | ASAC_0705 | ASAC_0953 | ABC transporter, ATP binding protein. | AAA family ATPase. | 0.777 |
| ASAC_0705 | pan | ASAC_0705 | ASAC_0295 | ABC transporter, ATP binding protein. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.681 |
| ASAC_0705 | psmA | ASAC_0705 | ASAC_1141 | ABC transporter, ATP binding protein. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.487 |
| ASAC_0705 | psmB | ASAC_0705 | ASAC_0316 | ABC transporter, ATP binding protein. | Proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.487 |
| ASAC_0705 | psmB-2 | ASAC_0705 | ASAC_0951 | ABC transporter, ATP binding protein. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.487 |
| ASAC_0705 | rpl40e | ASAC_0705 | ASAC_1109 | ABC transporter, ATP binding protein. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.543 |
| ASAC_0836 | ASAC_0705 | ASAC_0836 | ASAC_0705 | Predicted metalloprotease, containing Jab1/MPN domain. | ABC transporter, ATP binding protein. | 0.653 |
| ASAC_0836 | ASAC_0953 | ASAC_0836 | ASAC_0953 | Predicted metalloprotease, containing Jab1/MPN domain. | AAA family ATPase. | 0.670 |
| ASAC_0836 | ASAC_0957 | ASAC_0836 | ASAC_0957 | Predicted metalloprotease, containing Jab1/MPN domain. | DNA double-strand break repair rad50 ATPase. | 0.690 |
| ASAC_0836 | pan | ASAC_0836 | ASAC_0295 | Predicted metalloprotease, containing Jab1/MPN domain. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.983 |
| ASAC_0836 | psmA | ASAC_0836 | ASAC_1141 | Predicted metalloprotease, containing Jab1/MPN domain. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.842 |
| ASAC_0836 | psmB | ASAC_0836 | ASAC_0316 | Predicted metalloprotease, containing Jab1/MPN domain. | Proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.842 |
| ASAC_0836 | psmB-2 | ASAC_0836 | ASAC_0951 | Predicted metalloprotease, containing Jab1/MPN domain. | Proteasome beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.842 |
| ASAC_0836 | rpl40e | ASAC_0836 | ASAC_1109 | Predicted metalloprotease, containing Jab1/MPN domain. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.913 |
| ASAC_0910 | ASAC_0953 | ASAC_0910 | ASAC_0953 | Band 7 integral membrane protein-like protein. | AAA family ATPase. | 0.493 |
| ASAC_0910 | pan | ASAC_0910 | ASAC_0295 | Band 7 integral membrane protein-like protein. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.701 |
| ASAC_0953 | ASAC_0705 | ASAC_0953 | ASAC_0705 | AAA family ATPase. | ABC transporter, ATP binding protein. | 0.777 |
