Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metEProbable methylcobalamin:homocysteine methyltransferase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. (330 aa)    
Predicted Functional Partners:
ASAC_0322
Putative methylcobalamin:homocysteine methyltransferase.
 
  
0.992
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.978
ASAC_0864
Cystathionine gamma-lyase.
  
 
 0.958
ASAC_0793
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 
 0.924
metG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
    
 0.918
mat
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family.
     
 0.902
ASAC_1316
Threonine dehydratase.
  
 
 0.862
ASAC_0784
Hypothetical protein.
  
  
 0.860
ASAC_0324
Putative hydrogenase expression/formation protein HypE.
     
 0.811
ASAC_0273
Hypothetical protein.
  
    0.686
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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