Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ASAC_0472Hit histidine triad protein. (179 aa)    
Predicted Functional Partners:
sat
Sulfate adenylyltransferase; Belongs to the sulfate adenylyltransferase family.
    
 0.903
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
    
 0.903
radA
DNA repair and recombination protein radA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
  
  
 0.900
ASAC_0473
Predicted phosphohydrolase, DHH superfamily.
       0.827
ASAC_0471
Hypothetical protein.
       0.801
ASAC_0285
threonyl-tRNA synthetase.
    
 0.773
tbp
TATA-box-binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
 0.751
cobB
NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription; Belongs to the sirtuin family. Class U subfamily.
  
 
  0.678
lysS
lysyl-tRNA synthetase (LysS); Belongs to the class-II aminoacyl-tRNA synthetase family.
   
 0.640
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
    0.595
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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