Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ASAC_0817Isocitrate dehydrogenase (NADP+-dependent). (429 aa)    
Predicted Functional Partners:
ASAC_1330
Aconitase.
  
 0.997
ASAC_0288
Putative L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.985
ASAC_0871
Citrate synthase.
 
 0.980
sucC
Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.962
ASAC_1304
Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.957
ASAC_0875
Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit.
  
 
 0.922
ASAC_1291
Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit.
  
 
 0.922
ASAC_0874
Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit.
    
 0.917
ASAC_1292
Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit.
    
 0.917
sucD
Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.916
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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