Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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sucDSuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (293 aa)    
Predicted Functional Partners:
sucC
Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 0.999
ASAC_1440
Succinate:quinone oxidoreductase, iron-sulfur subunit B.
 
 0.995
ASAC_1443
Succinate:quinone oxidoreductase, flavoprotein subunit A.
 
 0.994
ASAC_1442
Succinate:quinone oxidoreductase, cytochrome b subunit C.
  
 
 0.988
ASAC_1441
Succinate:quinone oxidoreductase, hydrophobic anchor subunit D.
  
 
 0.966
prpB
Putative carboxyvinyl-carboxyphosphonate phosphorylmutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 0.936
ASAC_1078
Methylmalonyl-CoA mutase, C-terminal domain/subunit.
    
 0.932
ASAC_0874
Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit.
  
 
 0.931
ASAC_1292
Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit.
  
 
 0.931
ASAC_1077
Methylmalonyl-CoA mutase, N-terminal domain/subunit.
    
 0.928
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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