STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCSuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (382 aa)    
Predicted Functional Partners:
sucD
Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
ASAC_1442
Succinate:quinone oxidoreductase, cytochrome b subunit C.
  
 
 0.998
ASAC_0852
Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).
  
 0.997
ASAC_1441
Succinate:quinone oxidoreductase, hydrophobic anchor subunit D.
  
 
 0.995
ASAC_1443
Succinate:quinone oxidoreductase, flavoprotein subunit A.
 
 0.995
ASAC_1440
Succinate:quinone oxidoreductase, iron-sulfur subunit B.
 
 0.993
ASAC_0817
Isocitrate dehydrogenase (NADP+-dependent).
 
  
 0.986
ASAC_0871
Citrate synthase.
  
 
 0.972
ASAC_1077
Methylmalonyl-CoA mutase, N-terminal domain/subunit.
  
 
 0.940
ASAC_1078
Methylmalonyl-CoA mutase, C-terminal domain/subunit.
  
 
 0.940
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.