STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASAC_1077Methylmalonyl-CoA mutase, N-terminal domain/subunit. (566 aa)    
Predicted Functional Partners:
ASAC_1078
Methylmalonyl-CoA mutase, C-terminal domain/subunit.
 0.999
ASAC_1079
Transport system kinase.
  
 0.997
sucC
Succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.940
sucD
Succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.938
ASAC_0874
Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit.
    
 0.918
ASAC_0875
Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit.
    
 0.918
ASAC_1291
Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit.
    
 0.918
ASAC_1292
Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit.
    
 0.918
ASAC_0288
Putative L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
    
 0.854
ASAC_0852
Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).
  
 
 0.849
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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