Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fbpFructose-1,6-bisphosphatase (FBP); Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). (383 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
    
 0.992
gap
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH).
  
 
 0.984
ASAC_1207
Phosphoglucose isomerase (PGI).
  
  
 0.967
ASAC_0029
Fructose-1,6-bisphosphate aldolase.
    
 0.951
ASAC_0245
Glyceraldehyde-3-phosphate:ferredoxin oxidoreductase (GAPOR).
    
 0.951
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.930
ASAC_0880
Pyruvate kinase (PYK); Belongs to the pyruvate kinase family.
     
 0.926
ASAC_1423
Glyceraldehyde-3-phosphate dehydrogenase (non-phosphorylating) (GAPN).
    
 0.923
ASAC_0446
6-Phospho-3-hexuloisomerase (PHI).
     
 0.915
ASAC_0878
ADP-dependent hexokinase (HK).
    
 0.910
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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