Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (287 aa)    
Predicted Functional Partners:
ASAC_1244
Putative 2-dehydropantoate 2-reductase.
    
 0.994
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.841
ASAC_0275
Coenzyme A biosynthesis bifunctional protein CoaBC.
 
   
 0.699
ASAC_0272
DUF137 domain containing protein.
     
 0.583
ASAC_0270
ABC transporter, permease protein.
       0.561
ASAC_1245
Hypothetical protein.
       0.541
ASAC_0271
NatA-like ABC-type transport protein, ATPase component.
       0.525
ASAC_1365
Putative ketol-acid reductoisomerase 2.
     
 0.512
ASAC_0880
Pyruvate kinase (PYK); Belongs to the pyruvate kinase family.
     
 0.497
ASAC_1343
O-methyltransferase, family 3.
     
 0.463
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
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