STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ASAC_1371Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide E3 component-like enzyme; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (462 aa)    
Predicted Functional Partners:
ASAC_0852
Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase).
  
 0.998
gcvH
Probable glycine cleavage system H protein 1; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.978
ASAC_0569
Glycine cleavage system aminomethyltransferase T.
  
 0.974
ASAC_1235
Serine hydroxymethyltransferase.
 
 0.951
gcvPB
Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
  
 
 0.937
gcvPA
Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
  
 
 0.937
ASAC_0874
Putative 2-oxoacid:ferredoxin oxidoreductase, beta subunit.
    
 0.916
ASAC_1292
Putative 2-oxooglutarate:ferredoxin oxidoreductase (KGOR), beta subunit.
    
 0.916
ASAC_0875
Putative 2-oxoacid:ferredoxin oxidoreductase, alpha subunit.
  
 
 0.914
ASAC_1291
Putative 2-oxoglutarate:ferredoxin oxidoreductase (KGOR), alpha subunit.
  
 
 0.914
Your Current Organism:
Acidilobus saccharovorans
NCBI taxonomy Id: 666510
Other names: A. saccharovorans 345-15, Acidilobus saccharovorans 345-15, Acidilobus saccharovorans str. 345-15, Acidilobus saccharovorans strain 345-15, Acidilobus sp. 345-15
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.