node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M301_1073 | M301_1074 | M301_1073 | M301_1074 | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | KEGG: mmb:Mmol_1561 hypothetical protein. | 0.736 |
M301_1073 | M301_1075 | M301_1073 | M301_1075 | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | KEGG: mmb:Mmol_1560 FeS assembly protein IscX; TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528. | 0.702 |
M301_1073 | M301_1079 | M301_1073 | M301_1079 | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.463 |
M301_1073 | M301_2371 | M301_1073 | M301_2371 | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | KEGG: mmb:Mmol_1952 uncharacterized lipoprotein. | 0.449 |
M301_1073 | fabA | M301_1073 | M301_1094 | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. | 0.425 |
M301_1073 | glyA | M301_1073 | M301_1076 | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.466 |
M301_1073 | nrdR | M301_1073 | M301_1077 | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.454 |
M301_1074 | M301_1073 | M301_1074 | M301_1073 | KEGG: mmb:Mmol_1561 hypothetical protein. | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | 0.736 |
M301_1074 | M301_1075 | M301_1074 | M301_1075 | KEGG: mmb:Mmol_1561 hypothetical protein. | KEGG: mmb:Mmol_1560 FeS assembly protein IscX; TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528. | 0.749 |
M301_1074 | glyA | M301_1074 | M301_1076 | KEGG: mmb:Mmol_1561 hypothetical protein. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.497 |
M301_1074 | nrdR | M301_1074 | M301_1077 | KEGG: mmb:Mmol_1561 hypothetical protein. | ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.477 |
M301_1075 | M301_1073 | M301_1075 | M301_1073 | KEGG: mmb:Mmol_1560 FeS assembly protein IscX; TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528. | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | 0.702 |
M301_1075 | M301_1074 | M301_1075 | M301_1074 | KEGG: mmb:Mmol_1560 FeS assembly protein IscX; TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528. | KEGG: mmb:Mmol_1561 hypothetical protein. | 0.749 |
M301_1075 | glyA | M301_1075 | M301_1076 | KEGG: mmb:Mmol_1560 FeS assembly protein IscX; TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.523 |
M301_1075 | nrdR | M301_1075 | M301_1077 | KEGG: mmb:Mmol_1560 FeS assembly protein IscX; TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528. | ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.500 |
M301_1079 | M301_1073 | M301_1079 | M301_1073 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | 0.463 |
M301_1079 | glyA | M301_1079 | M301_1076 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.631 |
M301_1079 | nrdR | M301_1079 | M301_1077 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.832 |
M301_2371 | M301_1073 | M301_2371 | M301_1073 | KEGG: mmb:Mmol_1952 uncharacterized lipoprotein. | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | 0.449 |
fabA | M301_1073 | M301_1094 | M301_1073 | Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. | Peptidase A2A; KEGG: mmb:Mmol_1562 peptidase A2A. | 0.425 |