STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (394 aa)    
Predicted Functional Partners:
M301_2632
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.982
M301_0114
KEGG: mmb:Mmol_0796 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.981
metE
5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.972
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
 
  
 0.964
M301_1649
PFAM: aminotransferase class I and II; KEGG: cja:CJA_1896 aminotransferases class-I.
 
 
 0.955
M301_1204
PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: mmb:Mmol_1006 ferredoxin--nitrite reductase.
  
 0.945
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.935
M301_0792
PFAM: Flavocytochrome c sulphide dehydrogenase flavin-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mmb:Mmol_0670 flavocytochrome c sulphide dehydrogenase flavin-binding.
    
 0.905
M301_1100
KEGG: mmb:Mmol_1533 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein.
  
 
 0.903
M301_0791
PFAM: cytochrome c class I; KEGG: mmb:Mmol_0669 cytochrome c class I.
     
  0.900
Your Current Organism:
Methylotenera versatilis 301
NCBI taxonomy Id: 666681
Other names: M. versatilis 301, Methylotenera sp. 301, Methylotenera versatilis str. 301, Methylotenera versatilis strain 301
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