STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGK52192.1COG0789 Predicted transcriptional regulators. (108 aa)    
Predicted Functional Partners:
AGK53149.1
COG0174 Glutamine synthetase.
 
 
 0.833
AGK54086.1
COG0174 Glutamine synthetase.
 
 
 0.696
AGK53611.1
COG0174 Glutamine synthetase.
 
 
 0.676
AGK55819.1
Histidine kinase; COG0642 Signal transduction histidine kinase.
    
   0.674
AGK53634.1
Heat shock protein DnaJ domain-containing protein; COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain.
  
 
 0.599
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.560
AGK52907.1
Hypothetical protein; COG5503 Uncharacterized conserved small protein; Belongs to the UPF0356 family.
  
 
   0.541
AGK52191.1
Hypothetical protein.
       0.503
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.492
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
   0.478
Your Current Organism:
Bacillus sp. 1NLA3E
NCBI taxonomy Id: 666686
Other names: B. sp. 1NLA3E
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.