STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E9FRV3_DAPPUIsocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (408 aa)    
Predicted Functional Partners:
ACO1
Putative aconitate hydratase 1; Belongs to the aconitase/IPM isomerase family.
  
 0.994
E9GLV0_DAPPU
Transket_pyr domain-containing protein.
  
 
 0.992
ACN2
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.987
E9FY41_DAPPU
ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.979
E9FRE7_DAPPU
Citrate synthase; Belongs to the citrate synthase family.
  
 0.971
E9G2H1_DAPPU
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.971
E9GZ36_DAPPU
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.969
E9HRV4_DAPPU
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.969
E9FX71_DAPPU
Transket_pyr domain-containing protein.
  
 
 0.910
E9GAE4_DAPPU
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
  
 
0.901
Your Current Organism:
Daphnia pulex
NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.