RecQ1 protein (Daphnia pulex) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RecQ1

ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (624 aa)

Predicted Functional Partners:

RAD51C

0.737

E9H599_DAPPU

0.618

E9HR57_DAPPU

0.580

E9G1T4_DAPPU

0.574

E9GW86_DAPPU

0.566

E9FTZ6_DAPPU

0.549

E9GB55_DAPPU

0.533

E9GIE3_DAPPU

0.526

Rad21

0.513

Fen1

0.495

Your Current Organism:

Daphnia pulex

NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
E9FTZ6_DAPPU	E9GB55_DAPPU	E9FTZ6	E9GB55	Ku domain-containing protein.	Uncharacterized protein.	0.931
E9FTZ6_DAPPU	E9H599_DAPPU	E9FTZ6	E9H599	Ku domain-containing protein.	XPGI domain-containing protein.	0.909
E9FTZ6_DAPPU	E9HR57_DAPPU	E9FTZ6	E9HR57	Ku domain-containing protein.	Dna2 domain-containing protein.	0.742
E9FTZ6_DAPPU	Fen1	E9FTZ6	E9G8A4	Ku domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.779
E9FTZ6_DAPPU	RAD51C	E9FTZ6	E9GGD0	Ku domain-containing protein.	Putative RAD51C.	0.636
E9FTZ6_DAPPU	RecQ1	E9FTZ6	E9G2Y5	Ku domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.549
E9G1T4_DAPPU	RecQ1	E9G1T4	E9G2Y5	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.574
E9GB55_DAPPU	E9FTZ6_DAPPU	E9GB55	E9FTZ6	Uncharacterized protein.	Ku domain-containing protein.	0.931
E9GB55_DAPPU	E9H599_DAPPU	E9GB55	E9H599	Uncharacterized protein.	XPGI domain-containing protein.	0.905
E9GB55_DAPPU	E9HR57_DAPPU	E9GB55	E9HR57	Uncharacterized protein.	Dna2 domain-containing protein.	0.922
E9GB55_DAPPU	Fen1	E9GB55	E9G8A4	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.941
E9GB55_DAPPU	RAD51C	E9GB55	E9GGD0	Uncharacterized protein.	Putative RAD51C.	0.929
E9GB55_DAPPU	RecQ1	E9GB55	E9G2Y5	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.533
E9GIE3_DAPPU	E9GW86_DAPPU	E9GIE3	E9GW86	RNase_PH domain-containing protein.	Uncharacterized protein.	0.784
E9GIE3_DAPPU	RecQ1	E9GIE3	E9G2Y5	RNase_PH domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.526
E9GW86_DAPPU	E9GIE3_DAPPU	E9GW86	E9GIE3	Uncharacterized protein.	RNase_PH domain-containing protein.	0.784
E9GW86_DAPPU	RecQ1	E9GW86	E9G2Y5	Uncharacterized protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.566
E9H599_DAPPU	E9FTZ6_DAPPU	E9H599	E9FTZ6	XPGI domain-containing protein.	Ku domain-containing protein.	0.909
E9H599_DAPPU	E9GB55_DAPPU	E9H599	E9GB55	XPGI domain-containing protein.	Uncharacterized protein.	0.905
E9H599_DAPPU	E9HR57_DAPPU	E9H599	E9HR57	XPGI domain-containing protein.	Dna2 domain-containing protein.	0.974