STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E9GC36_DAPPUUncharacterized protein. (229 aa)    
Predicted Functional Partners:
E9GKZ0_DAPPU
Thymidylat_synt domain-containing protein.
  
  
 0.488
E9FT09_DAPPU
Structural maintenance of chromosomes protein.
   
 
 0.483
E9H1X3_DAPPU
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
   
 
 0.470
E9GF35_DAPPU
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.451
E9GU42_DAPPU
Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.
   
 
 0.439
E9G2B8_DAPPU
Uncharacterized protein.
   
 
 0.432
EOG090X0DZY
EOG090X0DZY; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.428
E9HC90_DAPPU
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.421
E9FZG7_DAPPU
Uncharacterized protein.
   
  
 0.406
Your Current Organism:
Daphnia pulex
NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.