STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E9HND8_DAPPU2-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (467 aa)    
Predicted Functional Partners:
E9H287_DAPPU
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.
   
0.989
E9FTC3_DAPPU
DPH-type MB domain-containing protein.
   
 0.975
E9H283_DAPPU
Tr-type G domain-containing protein.
    
 0.947
E9HLA8_DAPPU
TP_methylase domain-containing protein.
   
 0.932
E9FUY9_DAPPU
Tr-type G domain-containing protein.
    
 0.820
E9G149_DAPPU
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
    
 0.820
E9HJS5_DAPPU
Tr-type G domain-containing protein.
    
 0.820
E9HAZ0_DAPPU
RNA helicase.
   
   0.800
E9G172_DAPPU
WD_REPEATS_REGION domain-containing protein.
   
    0.766
E9H2Z1_DAPPU
Uncharacterized protein.
   
 
 0.673
Your Current Organism:
Daphnia pulex
NCBI taxonomy Id: 6669
Other names: D. pulex, common water flea
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