STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rsiWAnti-sigma factor; Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation (By similarity); Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. (221 aa)    
Predicted Functional Partners:
sigW
DNA-directed RNA polymerase ECF-type sigma factor sigma-W; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.955
prsW
Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).
  
   
 0.802
ABC2674
Conserved hypothetical protein.
  
     0.772
sigY
DNA-directed RNA polymerase ECF-type sigma factor sigma-Y; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.709
ABC2684
Conserved hypothetical protein.
  
  
 0.699
ABC2946
Conserved hypothetical protein.
 
     0.682
sigV
DNA-directed RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.678
ABC0036
DNA-directed RNA polymerase ECF-type sigma factor; Belongs to the sigma-70 factor family. ECF subfamily.
 
 
 0.677
ABC4052
Hypothetical protein.
 
 
 0.662
ABC0242
Conserved hypothetical protein.
 
     0.629
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.