STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolFMajor facilitator superfamily (MFS) family inositol transporter. (424 aa)    
Predicted Functional Partners:
rhaM
Conserved hypothetical protein; Involved in the anomeric conversion of L-rhamnose.
 
   
 0.942
iolE
Myo-inositol catabolism protein IolE; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).
  
    0.806
rhaAB
Rhamnulokinase and L-rhamnose isomerase; In the N-terminal section; belongs to the rhamnulokinase family.
 
  
 0.774
iolB
Myo-inositol catabolism protein IolB; Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).
  
  
 0.766
iolD
Myo-inositol catabolism protein IolD; Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
  
  
 0.760
ABC0375
Conserved hypothetical protein.
 
     0.691
ABC0378
AraC/XylS family transcriptional regulator.
       0.493
ABC0381
Sugar phosphate isomerases/epimerase.
 
    0.463
ABC0379
Oxidoreductase.
 
    0.441
ABC0380
Conserved hypothetical protein.
 
     0.435
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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