STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
iolAMethylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. (491 aa)    
Predicted Functional Partners:
iolJ
Fructose-bisphosphate aldolase; Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6- phospho-5-dehydro-2-deoxy-D-gluconate (DKGP); Belongs to the class II fructose-bisphosphate aldolase family. IolJ subfamily.
  
 
 0.930
gabT
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.927
citZ
Citrate synthase II; Belongs to the citrate synthase family.
  
 0.925
ABC2989
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.922
ABC1808
3-hydroxyisobutyrate dehydrogenase.
 
 
 0.920
ABC2572
propionyl-CoA carboxylase beta chain.
   
 
 0.920
bkdB
Branched-chain alpha-keto acid dehydrogenase E2 component.
  
 
 0.919
ABC1279
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 
0.916
dhaS
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.915
acsA
Acetyl-coenzyme A synthetase.
  
 0.911
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.