STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABC0751Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (270 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.944
hisC
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.934
hisJ
Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
  
  
 
0.920
hisB
Imidazoleglycerol-phosphate dehydratase.
  
  
 0.845
ABC1168
Histidinol dehydrogenase.
  
 
 0.696
hisH
Imidazole glycerol phosphate synthase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
    0.688
hisI
Bifunctional histidine biosynthesis protein HisJ; phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.662
ABC0750
Oxidoreductase; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
  
    0.512
ABC0752
Minor extracellular serine protease; Belongs to the peptidase S8 family.
  
    0.449
ybeY
Metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
    0.433
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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