STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aprEExtracellular alkaline serine protease. (380 aa)    
Predicted Functional Partners:
sapB
Magnesium transporter.
  
   
 0.612
sigF
DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
  
 0.595
dnaI
Primosome component DnaI.
      
 0.589
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
 0.553
ABC3151
Dehydrogenase.
   
  
 0.547
ABC3276
Dehydrogenase.
   
  
 0.547
ABC3277
Dehydrogenase.
   
  
 0.547
xylA
Xylose isomerase; Belongs to the xylose isomerase family.
      
 0.546
ampS
Aminopeptidase.
      
 0.546
ABC3687
O-antigen transporter.
      
 0.545
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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