rsbX protein (Bacillus clausii) - STRING interaction network

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Score

rsbX

Indirect negative regulator of sigma-B activity. (208 aa)

Predicted Functional Partners:

rsbT

0.995

rsbS

0.994

rsbR

0.988

rsbU

0.977

rsbW

0.975

ABC3461

0.919

sigB

0.897

rsbV

0.843

obg

0.715

spoIIAB

0.710

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABC3461	rsbS	ABC3461	ABC0811	Anti-anti-sigma regulatory factor.	Negative regulator of sigma-B activity.	0.855
ABC3461	rsbT	ABC3461	ABC0812	Anti-anti-sigma regulatory factor.	Positive regulator of sigma-B activity.	0.962
ABC3461	rsbU	ABC3461	ABC0813	Anti-anti-sigma regulatory factor.	Indirect positive regulator of sigma-B activity.	0.780
ABC3461	rsbW	ABC3461	ABC0815	Anti-anti-sigma regulatory factor.	Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).	0.815
ABC3461	rsbX	ABC3461	ABC0817	Anti-anti-sigma regulatory factor.	Indirect negative regulator of sigma-B activity.	0.919
ABC3461	spoIIAB	ABC3461	ABC1794	Anti-anti-sigma regulatory factor.	Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.767
obg	rsbS	ABC1542	ABC0811	Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Negative regulator of sigma-B activity.	0.712
obg	rsbT	ABC1542	ABC0812	Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Positive regulator of sigma-B activity.	0.718
obg	rsbU	ABC1542	ABC0813	Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Indirect positive regulator of sigma-B activity.	0.418
obg	rsbW	ABC1542	ABC0815	Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).	0.432
obg	rsbX	ABC1542	ABC0817	Spo0B-associated GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.	Indirect negative regulator of sigma-B activity.	0.715
rsbR	rsbS	ABC0810	ABC0811	Positive regulator of sigma-B activity.	Negative regulator of sigma-B activity.	0.995
rsbR	rsbT	ABC0810	ABC0812	Positive regulator of sigma-B activity.	Positive regulator of sigma-B activity.	0.995
rsbR	rsbU	ABC0810	ABC0813	Positive regulator of sigma-B activity.	Indirect positive regulator of sigma-B activity.	0.982
rsbR	rsbV	ABC0810	ABC0814	Positive regulator of sigma-B activity.	Positive regulator of sigma-B activity; Belongs to the anti-sigma-factor antagonist family.	0.718
rsbR	rsbW	ABC0810	ABC0815	Positive regulator of sigma-B activity.	Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).	0.922
rsbR	rsbX	ABC0810	ABC0817	Positive regulator of sigma-B activity.	Indirect negative regulator of sigma-B activity.	0.988
rsbR	sigB	ABC0810	ABC0816	Positive regulator of sigma-B activity.	DNA-directed RNA polymerase general stress sigma factor sigma-B; Belongs to the sigma-70 factor family.	0.798
rsbR	spoIIAB	ABC0810	ABC1794	Positive regulator of sigma-B activity.	Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.767
rsbS	ABC3461	ABC0811	ABC3461	Negative regulator of sigma-B activity.	Anti-anti-sigma regulatory factor.	0.855