Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABC1076Conserved hypothetical protein. (102 aa)    
Predicted Functional Partners:
ABC1075
Adenine deaminase.
       0.581
hisI
Bifunctional histidine biosynthesis protein HisJ; phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
 
   
 0.561
pcrB
PcrB protein; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
 
     0.525
adeC
Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
       0.516
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
       0.472
fapR
Conserved hypothetical protein; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
  
     0.430
ahrC
Transcriptional regulator of arginine metabolism expression; Regulates arginine biosynthesis genes.
  
   
 0.429
pcrA
UvrD/REP family ATP-dependent DNA helicase.
       0.411
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
       0.411
ABC1088
Conserved hypothetical protein.
       0.411
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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