Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
perRFur family transcriptional regulator; Belongs to the Fur family. (143 aa)    
Predicted Functional Partners:
ABC2428
2-cys peroxiredoxin.
  
  
 0.742
ABC1990
Conserved hypothetical protein.
  
    0.729
ABC1320
Conserved hypothetical protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
     0.705
ABC1319
Bacterioferritin comigratory protein BCP.
     
 0.681
spxA
Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
  
 0.660
ABC1321
Conserved hypothetical protein.
       0.640
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.622
mntR
Manganese transport regulator; Central regulator of manganese homeostasis. Belongs to the DtxR/MntR family.
  
  
 0.569
ABC3173
DeoR family transcriptional regulator.
  
    0.546
trxA
Thioredoxin; Belongs to the thioredoxin family.
  
 
 0.484
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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