mtnV protein (Bacillus clausii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

mtnV

Aspartate aminotransferase. (390 aa)

Predicted Functional Partners:

ABC1868

0.945

metK

0.931

ABC1869

0.929

metC

0.918

ABC3938

0.918

mtnU

0.915

ABC0432

0.909

ABC2756

0.900

mtnW

0.855

nfrA1

0.816

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABC0432	ABC1868	ABC0432	ABC1868	O-acetylhomoserine (thiol)-lyase.	5,10-methylenetetrahydrofolate reductase.	0.972
ABC0432	ABC1869	ABC0432	ABC1869	O-acetylhomoserine (thiol)-lyase.	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.979
ABC0432	ABC2756	ABC0432	ABC2756	O-acetylhomoserine (thiol)-lyase.	GAF domain-containing protein; Probable gene remnant. Similar to the region between codons 156 and 205 of Bacillus anthracis transposase, IS605 family BA3745 (370 aa) TR:Q81Y14; locus_tag:ABC2754.	0.902
ABC0432	ABC3938	ABC0432	ABC3938	O-acetylhomoserine (thiol)-lyase.	Methionine gamma-lyase.	0.934
ABC0432	metC	ABC0432	ABC1449	O-acetylhomoserine (thiol)-lyase.	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.923
ABC0432	metK	ABC0432	ABC2878	O-acetylhomoserine (thiol)-lyase.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.919
ABC0432	mtnV	ABC0432	ABC1492	O-acetylhomoserine (thiol)-lyase.	Aspartate aminotransferase.	0.909
ABC0432	mtnW	ABC0432	ABC1775	O-acetylhomoserine (thiol)-lyase.	Ribulose bisphosphate carboxylase; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily.	0.670
ABC1868	ABC0432	ABC1868	ABC0432	5,10-methylenetetrahydrofolate reductase.	O-acetylhomoserine (thiol)-lyase.	0.972
ABC1868	ABC1869	ABC1868	ABC1869	5,10-methylenetetrahydrofolate reductase.	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.999
ABC1868	ABC2756	ABC1868	ABC2756	5,10-methylenetetrahydrofolate reductase.	GAF domain-containing protein; Probable gene remnant. Similar to the region between codons 156 and 205 of Bacillus anthracis transposase, IS605 family BA3745 (370 aa) TR:Q81Y14; locus_tag:ABC2754.	0.903
ABC1868	ABC3938	ABC1868	ABC3938	5,10-methylenetetrahydrofolate reductase.	Methionine gamma-lyase.	0.980
ABC1868	metC	ABC1868	ABC1449	5,10-methylenetetrahydrofolate reductase.	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.996
ABC1868	metK	ABC1868	ABC2878	5,10-methylenetetrahydrofolate reductase.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.992
ABC1868	mtnV	ABC1868	ABC1492	5,10-methylenetetrahydrofolate reductase.	Aspartate aminotransferase.	0.945
ABC1868	mtnW	ABC1868	ABC1775	5,10-methylenetetrahydrofolate reductase.	Ribulose bisphosphate carboxylase; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily.	0.848
ABC1869	ABC0432	ABC1869	ABC0432	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	O-acetylhomoserine (thiol)-lyase.	0.979
ABC1869	ABC1868	ABC1869	ABC1868	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	5,10-methylenetetrahydrofolate reductase.	0.999
ABC1869	ABC2756	ABC1869	ABC2756	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	GAF domain-containing protein; Probable gene remnant. Similar to the region between codons 156 and 205 of Bacillus anthracis transposase, IS605 family BA3745 (370 aa) TR:Q81Y14; locus_tag:ABC2754.	0.900
ABC1869	ABC3938	ABC1869	ABC3938	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Methionine gamma-lyase.	0.959