ecsB protein (Bacillus clausii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ecsB

Multidrug ABC transporter permease. (408 aa)

Predicted Functional Partners:

ecsA

0.978

ABC1535

0.943

ABC1532

0.720

ABC2767

0.714

ABC2626

0.692

ABC2381

0.680

ABC2741

0.678

mecA-2

0.668

ABC2948

0.660

ABC0820

0.655

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABC0820	ABC2741	ABC0820	ABC2741	SprT family metallopeptidase; Belongs to the SprT family.	Adenine-specific methyltransferase.	0.484
ABC0820	ABC2948	ABC0820	ABC2948	SprT family metallopeptidase; Belongs to the SprT family.	Conserved hypothetical protein.	0.513
ABC0820	ecsB	ABC0820	ABC1534	SprT family metallopeptidase; Belongs to the SprT family.	Multidrug ABC transporter permease.	0.655
ABC1532	ABC1535	ABC1532	ABC1535	Hit family cell-cycle regulation histidine triad.	Conserved hypothetical protein.	0.567
ABC1532	ecsA	ABC1532	ABC1533	Hit family cell-cycle regulation histidine triad.	Multidrug ABC transporter ATP-binding protein.	0.818
ABC1532	ecsB	ABC1532	ABC1534	Hit family cell-cycle regulation histidine triad.	Multidrug ABC transporter permease.	0.720
ABC1535	ABC1532	ABC1535	ABC1532	Conserved hypothetical protein.	Hit family cell-cycle regulation histidine triad.	0.567
ABC1535	ecsA	ABC1535	ABC1533	Conserved hypothetical protein.	Multidrug ABC transporter ATP-binding protein.	0.917
ABC1535	ecsB	ABC1535	ABC1534	Conserved hypothetical protein.	Multidrug ABC transporter permease.	0.943
ABC2381	ABC2767	ABC2381	ABC2767	Conserved hypothetical protein; Belongs to the UPF0342 family.	General stress protein.	0.491
ABC2381	ABC2948	ABC2381	ABC2948	Conserved hypothetical protein; Belongs to the UPF0342 family.	Conserved hypothetical protein.	0.585
ABC2381	ecsB	ABC2381	ABC1534	Conserved hypothetical protein; Belongs to the UPF0342 family.	Multidrug ABC transporter permease.	0.680
ABC2381	mecA-2	ABC2381	ABC2527	Conserved hypothetical protein; Belongs to the UPF0342 family.	Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.	0.565
ABC2626	ecsB	ABC2626	ABC1534	Stage VI sporulation protein D.	Multidrug ABC transporter permease.	0.692
ABC2741	ABC0820	ABC2741	ABC0820	Adenine-specific methyltransferase.	SprT family metallopeptidase; Belongs to the SprT family.	0.484
ABC2741	ABC2767	ABC2741	ABC2767	Adenine-specific methyltransferase.	General stress protein.	0.715
ABC2741	ABC2948	ABC2741	ABC2948	Adenine-specific methyltransferase.	Conserved hypothetical protein.	0.556
ABC2741	ecsB	ABC2741	ABC1534	Adenine-specific methyltransferase.	Multidrug ABC transporter permease.	0.678
ABC2741	mecA-2	ABC2741	ABC2527	Adenine-specific methyltransferase.	Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.	0.565
ABC2767	ABC2381	ABC2767	ABC2381	General stress protein.	Conserved hypothetical protein; Belongs to the UPF0342 family.	0.491