STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
dacFD-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (388 aa)    
Predicted Functional Partners:
ABC1175
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
 
  
 
0.927
dacB
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
 
  
 
0.923
pbpF
Penicillin-binding protein.
  
 
 0.920
ponA
Penicillin-binding protein 1A/1B; Penicillin-sensitive transpeptidase, PBP1.
  
 
 0.920
dacA
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
  
 
0.916
ABC2759
Penicillin-binding protein 1A.
  
 
 0.916
ABC0801
D-alanyl-D-alanine carboxypeptidase.
    
 0.912
spoIIAB
Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.830
sigF
DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.792
spoIIAA
Stage II sporulation protein AA, anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
   
 0.742
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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