| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dacF | sigF | ABC1792 | ABC1795 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.792 |
| dacF | spoIIAA | ABC1792 | ABC1793 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Stage II sporulation protein AA, anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.742 |
| dacF | spoIIAB | ABC1792 | ABC1794 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.830 |
| dacF | spoIIGA | ABC1792 | ABC2352 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.460 |
| dacF | spoIIP | ABC1792 | ABC1653 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Stage II sporulation protein P; Septal wall dissolution protein. | 0.487 |
| dacF | spoIIR | ABC1792 | ABC3872 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Stage II sporulation protein R. | 0.450 |
| dacF | spoVAF | ABC1792 | ABC1800 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Stage V sporulation protein AF. | 0.523 |
| rsbW | sigB | ABC0815 | ABC0816 | Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | DNA-directed RNA polymerase general stress sigma factor sigma-B; Belongs to the sigma-70 factor family. | 0.976 |
| rsbW | sigF | ABC0815 | ABC1795 | Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.726 |
| rsbW | spoIIAA | ABC0815 | ABC1793 | Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | Stage II sporulation protein AA, anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.973 |
| rsbW | spoIIGA | ABC0815 | ABC2352 | Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.581 |
| sigB | rsbW | ABC0816 | ABC0815 | DNA-directed RNA polymerase general stress sigma factor sigma-B; Belongs to the sigma-70 factor family. | Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.976 |
| sigB | spoIIAA | ABC0816 | ABC1793 | DNA-directed RNA polymerase general stress sigma factor sigma-B; Belongs to the sigma-70 factor family. | Stage II sporulation protein AA, anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.823 |
| sigB | spoIIAB | ABC0816 | ABC1794 | DNA-directed RNA polymerase general stress sigma factor sigma-B; Belongs to the sigma-70 factor family. | Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.673 |
| sigB | spoIIGA | ABC0816 | ABC2352 | DNA-directed RNA polymerase general stress sigma factor sigma-B; Belongs to the sigma-70 factor family. | Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.405 |
| sigF | dacF | ABC1795 | ABC1792 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.792 |
| sigF | rsbW | ABC1795 | ABC0815 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Anti-sigma B factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.726 |
| sigF | spoIIAA | ABC1795 | ABC1793 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein AA, anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.997 |
| sigF | spoIIAB | ABC1795 | ABC1794 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.994 |
| sigF | spoIIE | ABC1795 | ABC0101 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Serine phosphatase stage II sporulation protein E. | 0.772 |