| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABC1675 | sigF | ABC1675 | ABC1795 | Stage IV sporulation protein. | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.653 |
| ABC1675 | sigG | ABC1675 | ABC2350 | Stage IV sporulation protein. | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.732 |
| ABC1675 | spo0A | ABC1675 | ABC2457 | Stage IV sporulation protein. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.423 |
| ABC1675 | spoIIAA | ABC1675 | ABC1793 | Stage IV sporulation protein. | Stage II sporulation protein AA, anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.543 |
| ABC1675 | spoIIAB | ABC1675 | ABC1794 | Stage IV sporulation protein. | Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.878 |
| ABC1675 | spoIIE | ABC1675 | ABC0101 | Stage IV sporulation protein. | Serine phosphatase stage II sporulation protein E. | 0.768 |
| ABC1675 | spoIIGA | ABC1675 | ABC2352 | Stage IV sporulation protein. | Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.837 |
| ABC1675 | spoIIID | ABC1675 | ABC3842 | Stage IV sporulation protein. | Stage III sporulation protein D. | 0.843 |
| ABC1675 | spoIIR | ABC1675 | ABC3872 | Stage IV sporulation protein. | Stage II sporulation protein R. | 0.862 |
| ABC1675 | spoVAF | ABC1675 | ABC1800 | Stage IV sporulation protein. | Stage V sporulation protein AF. | 0.692 |
| sigF | ABC1675 | ABC1795 | ABC1675 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein. | 0.653 |
| sigF | spo0A | ABC1795 | ABC2457 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.893 |
| sigF | spoIIAA | ABC1795 | ABC1793 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein AA, anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family. | 0.997 |
| sigF | spoIIAB | ABC1795 | ABC1794 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.994 |
| sigF | spoIIE | ABC1795 | ABC0101 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Serine phosphatase stage II sporulation protein E. | 0.772 |
| sigF | spoIIGA | ABC1795 | ABC2352 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.773 |
| sigF | spoIIID | ABC1795 | ABC3842 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein D. | 0.810 |
| sigF | spoIIR | ABC1795 | ABC3872 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein R. | 0.762 |
| sigF | spoVAF | ABC1795 | ABC1800 | DNA-directed RNA polymerase sigma factor sigma-F; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage V sporulation protein AF. | 0.872 |
| sigG | ABC1675 | ABC2350 | ABC1675 | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage IV sporulation protein. | 0.732 |