STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribBRiboflavin synthase alpha subunit RibB. (214 aa)    
Predicted Functional Partners:
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
 
 0.999
ribH
Riboflavin synthase beta subunit RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
 
 0.999
ribG
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 0.999
ribC
Riboflavin biosynthesis protein RibC; FMN adenylyltransferase; Belongs to the ribF family.
  
 
 0.938
ABC2560
HAD superfamily hydrolase.
     
 0.915
ABC2088
HAD superfamily hydrolase.
     
 0.901
ABC3962
HAD superfamily hydrolase.
     
 0.901
hisI
Bifunctional histidine biosynthesis protein HisJ; phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
  
    0.817
rpmE
50S ribosomal protein L31.
   
    0.679
ABC1389
NADH peroxidase; Probable gene remnant. Similar to the N-terminal region of Mesorhizobium loti oxidoreductase of short-chain mlr1899 (278 aa) TR:Q98JK8; locus_tag:ABC1388.
   
    0.509
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
Server load: low (32%) [HD]