node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABC0679 | ABC1857 | ABC0679 | ABC1857 | Conserved hypothetical protein. | MarR family transcriptional regulator. | 0.471 |
ABC1856 | ABC1857 | ABC1856 | ABC1857 | Phosphohydrolase. | MarR family transcriptional regulator. | 0.769 |
ABC1856 | mecA | ABC1856 | ABC1858 | Phosphohydrolase. | Negative regulator of genetic competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.527 |
ABC1857 | ABC0679 | ABC1857 | ABC0679 | MarR family transcriptional regulator. | Conserved hypothetical protein. | 0.471 |
ABC1857 | ABC1856 | ABC1857 | ABC1856 | MarR family transcriptional regulator. | Phosphohydrolase. | 0.769 |
ABC1857 | ABC1860 | ABC1857 | ABC1860 | MarR family transcriptional regulator. | Two-component sensor histidine kinase. | 0.487 |
ABC1857 | ABC1868 | ABC1857 | ABC1868 | MarR family transcriptional regulator. | 5,10-methylenetetrahydrofolate reductase. | 0.653 |
ABC1857 | ABC1869 | ABC1857 | ABC1869 | MarR family transcriptional regulator. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.712 |
ABC1857 | ABC2116 | ABC1857 | ABC2116 | MarR family transcriptional regulator. | Hypothetical protein. | 0.639 |
ABC1857 | dnaJ | ABC1857 | ABC1660 | MarR family transcriptional regulator. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.471 |
ABC1857 | dra | ABC1857 | ABC1666 | MarR family transcriptional regulator. | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.815 |
ABC1857 | hemE | ABC1857 | ABC1538 | MarR family transcriptional regulator. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.504 |
ABC1857 | mecA | ABC1857 | ABC1858 | MarR family transcriptional regulator. | Negative regulator of genetic competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.571 |
ABC1860 | ABC1857 | ABC1860 | ABC1857 | Two-component sensor histidine kinase. | MarR family transcriptional regulator. | 0.487 |
ABC1860 | mecA | ABC1860 | ABC1858 | Two-component sensor histidine kinase. | Negative regulator of genetic competence; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | 0.511 |
ABC1868 | ABC1857 | ABC1868 | ABC1857 | 5,10-methylenetetrahydrofolate reductase. | MarR family transcriptional regulator. | 0.653 |
ABC1868 | ABC1869 | ABC1868 | ABC1869 | 5,10-methylenetetrahydrofolate reductase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
ABC1868 | hemE | ABC1868 | ABC1538 | 5,10-methylenetetrahydrofolate reductase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.485 |
ABC1869 | ABC1857 | ABC1869 | ABC1857 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | MarR family transcriptional regulator. | 0.712 |
ABC1869 | ABC1868 | ABC1869 | ABC1868 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 5,10-methylenetetrahydrofolate reductase. | 0.999 |