| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABC0432 | ABC1868 | ABC0432 | ABC1868 | O-acetylhomoserine (thiol)-lyase. | 5,10-methylenetetrahydrofolate reductase. | 0.972 |
| ABC0432 | ABC1869 | ABC0432 | ABC1869 | O-acetylhomoserine (thiol)-lyase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.979 |
| ABC0432 | ABC1944 | ABC0432 | ABC1944 | O-acetylhomoserine (thiol)-lyase. | Cysteine synthase. | 0.919 |
| ABC0432 | ABC2792 | ABC0432 | ABC2792 | O-acetylhomoserine (thiol)-lyase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.839 |
| ABC0432 | cysJ | ABC0432 | ABC0619 | O-acetylhomoserine (thiol)-lyase. | Sulfite reductase hemoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.532 |
| ABC0432 | cysK | ABC0432 | ABC0109 | O-acetylhomoserine (thiol)-lyase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.839 |
| ABC0432 | metAA | ABC0432 | ABC2149 | O-acetylhomoserine (thiol)-lyase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.969 |
| ABC0432 | metC | ABC0432 | ABC1449 | O-acetylhomoserine (thiol)-lyase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.923 |
| ABC0432 | metI | ABC0432 | ABC1867 | O-acetylhomoserine (thiol)-lyase. | Cystathionine gamma-synthase. | 0.933 |
| ABC0432 | patB | ABC0432 | ABC2888 | O-acetylhomoserine (thiol)-lyase. | Aminotransferase. | 0.922 |
| ABC1868 | ABC0432 | ABC1868 | ABC0432 | 5,10-methylenetetrahydrofolate reductase. | O-acetylhomoserine (thiol)-lyase. | 0.972 |
| ABC1868 | ABC1869 | ABC1868 | ABC1869 | 5,10-methylenetetrahydrofolate reductase. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
| ABC1868 | ABC1944 | ABC1868 | ABC1944 | 5,10-methylenetetrahydrofolate reductase. | Cysteine synthase. | 0.935 |
| ABC1868 | ABC2792 | ABC1868 | ABC2792 | 5,10-methylenetetrahydrofolate reductase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.871 |
| ABC1868 | cysJ | ABC1868 | ABC0619 | 5,10-methylenetetrahydrofolate reductase. | Sulfite reductase hemoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.563 |
| ABC1868 | cysK | ABC1868 | ABC0109 | 5,10-methylenetetrahydrofolate reductase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.871 |
| ABC1868 | metAA | ABC1868 | ABC2149 | 5,10-methylenetetrahydrofolate reductase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.981 |
| ABC1868 | metC | ABC1868 | ABC1449 | 5,10-methylenetetrahydrofolate reductase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.996 |
| ABC1868 | metI | ABC1868 | ABC1867 | 5,10-methylenetetrahydrofolate reductase. | Cystathionine gamma-synthase. | 0.995 |
| ABC1868 | patB | ABC1868 | ABC2888 | 5,10-methylenetetrahydrofolate reductase. | Aminotransferase. | 0.941 |