| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cotE | gpr | ABC2188 | ABC1652 | Spore coat protein E. | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.457 |
| cotE | spoIIID | ABC2188 | ABC3842 | Spore coat protein E. | Stage III sporulation protein D. | 0.667 |
| cotE | spoIIP | ABC2188 | ABC1653 | Spore coat protein E. | Stage II sporulation protein P; Septal wall dissolution protein. | 0.712 |
| cotE | spoIVA | ABC2188 | ABC1882 | Spore coat protein E. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.825 |
| gpr | cotE | ABC1652 | ABC2188 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Spore coat protein E. | 0.457 |
| gpr | sigG | ABC1652 | ABC2350 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.767 |
| gpr | spoIIAB | ABC1652 | ABC1794 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.785 |
| gpr | spoIIGA | ABC1652 | ABC2352 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.747 |
| gpr | spoIIIAA | ABC1652 | ABC2478 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage III sporulation protein AA. | 0.753 |
| gpr | spoIIIAD | ABC1652 | ABC2475 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage III sporulation protein AD. | 0.772 |
| gpr | spoIIID | ABC1652 | ABC3842 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage III sporulation protein D. | 0.770 |
| gpr | spoIIP | ABC1652 | ABC1653 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein P; Septal wall dissolution protein. | 0.890 |
| gpr | spoIIR | ABC1652 | ABC3872 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein R. | 0.773 |
| gpr | spoIVA | ABC1652 | ABC1882 | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.806 |
| sigG | gpr | ABC2350 | ABC1652 | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Germination protease precursor; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.767 |
| sigG | spoIIAB | ABC2350 | ABC1794 | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage II sporulation protein AB; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.909 |
| sigG | spoIIGA | ABC2350 | ABC2352 | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. | 0.857 |
| sigG | spoIIIAA | ABC2350 | ABC2478 | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein AA. | 0.765 |
| sigG | spoIIIAD | ABC2350 | ABC2475 | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein AD. | 0.766 |
| sigG | spoIIID | ABC2350 | ABC3842 | DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Stage III sporulation protein D. | 0.815 |