Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
spoIVAStage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)    
Predicted Functional Partners:
spoIIIAD
Stage III sporulation protein AD.
  
  
 0.958
cotE
Spore coat protein E.
  
  
 0.943
spoIIIAA
Stage III sporulation protein AA.
  
  
 0.905
spoIIID
Stage III sporulation protein D.
  
  
 0.881
spoIID
Stage II sporulation protein D.
  
  
 0.880
cwlJ
Cell wall hydrolase.
  
   
 0.870
spoIIIAC
Stage III sporulation protein AC.
  
  
 0.862
spoIIP
Stage II sporulation protein P; Septal wall dissolution protein.
 
   
 0.851
spo0A
Stage 0 sporulation protein A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.840
spoIIIAB
Stage III sporulation protein AB.
  
  
 0.834
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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