STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ponAPenicillin-binding protein 1A/1B; Penicillin-sensitive transpeptidase, PBP1. (935 aa)    
Predicted Functional Partners:
ABC2759
Penicillin-binding protein 1A.
  
  
 
0.927
pbpF
Penicillin-binding protein.
  
  
 
0.920
dacF
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.920
dacA
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.914
ABC0801
D-alanyl-D-alanine carboxypeptidase.
     
 0.906
ABC1175
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.905
dacB
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
  
 
 0.905
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
 
  
 0.854
gpsB
Cell division initiation protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
 
 
 0.836
cwlC
N-acetylmuramoyl-L-alanine amidase.
 
 
 
 0.800
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.