STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoVSStage V sporulation protein S. (87 aa)    
Predicted Functional Partners:
spoIIIAC
Stage III sporulation protein AC.
      
 0.625
spoIIM
Stage II sporulation protein M; Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.
  
   
 0.615
etfA
Electron transfer flavoprotein alpha subunit.
      
 0.595
smpB
ssrA RNA (tmRNA)-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then [...]
      
 0.588
spoVG
Stage V sporulation protein G; Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation.
      
 0.583
ABC2193
Conserved hypothetical protein.
  
    0.576
rny
HAD superfamily hydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
     0.570
spoVR
Stage V sporulation protein R.
      
 0.563
spoIIID
Stage III sporulation protein D.
      
 0.555
bofA
Inhibition of the pro-sigma-K processing machinery.
      
 0.514
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.