| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABC0756 | phoB | ABC0756 | ABC3952 | Transcriptional activator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | 0.900 |
| ABC0756 | rsgA | ABC0756 | ABC2314 | Transcriptional activator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.900 |
| ABC0756 | tenA | ABC0756 | ABC0669 | Transcriptional activator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Transcriptional activator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | 0.911 |
| ABC0756 | thiC | ABC0756 | ABC1733 | Transcriptional activator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.859 |
| adk | rpsL | ABC0171 | ABC0145 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.533 |
| adk | rsgA | ABC0171 | ABC2314 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.900 |
| adk | thiL | ABC0171 | ABC0867 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.900 |
| phoB | ABC0756 | ABC3952 | ABC0756 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | Transcriptional activator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. | 0.900 |
| phoB | rsgA | ABC3952 | ABC2314 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.900 |
| phoB | tenA | ABC3952 | ABC0669 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | Transcriptional activator of extracellular enzyme genes; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | 0.900 |
| phoB | thiC | ABC3952 | ABC1733 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.902 |
| phoB | thiL | ABC3952 | ABC0867 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.900 |
| prkC | prpC | ABC2315 | ABC2316 | Serine/threonine protein kinase. | Serine/threonine protein phosphatase. | 0.998 |
| prkC | rpe | ABC2315 | ABC2313 | Serine/threonine protein kinase. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.704 |
| prkC | rsgA | ABC2315 | ABC2314 | Serine/threonine protein kinase. | GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.879 |
| prpC | prkC | ABC2316 | ABC2315 | Serine/threonine protein phosphatase. | Serine/threonine protein kinase. | 0.998 |
| prpC | rpe | ABC2316 | ABC2313 | Serine/threonine protein phosphatase. | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | 0.675 |
| prpC | rsgA | ABC2316 | ABC2314 | Serine/threonine protein phosphatase. | GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.866 |
| rpe | prkC | ABC2313 | ABC2315 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Serine/threonine protein kinase. | 0.704 |
| rpe | prpC | ABC2313 | ABC2316 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. | Serine/threonine protein phosphatase. | 0.675 |