gmk protein (Bacillus clausii) - STRING interaction network

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gmk

Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (205 aa)

Predicted Functional Partners:

ABC2323

0.981

guaA

0.979

hprT

0.968

xpt

0.963

rpoZ

0.962

relA

0.930

guaC

0.930

ndk

0.925

dgk

0.923

purB

0.921

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABC2323	gmk	ABC2323	ABC2322	Conserved hypothetical protein; Belongs to the RemA family.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.981
ABC2323	rpoZ	ABC2323	ABC2321	Conserved hypothetical protein; Belongs to the RemA family.	DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.840
dgk	gmk	ABC2889	ABC2322	Deoxypurine kinase.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.923
gmk	ABC2323	ABC2322	ABC2323	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Conserved hypothetical protein; Belongs to the RemA family.	0.981
gmk	dgk	ABC2322	ABC2889	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Deoxypurine kinase.	0.923
gmk	guaA	ABC2322	ABC0936	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	0.979
gmk	guaC	ABC2322	ABC3216	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.	0.930
gmk	hprT	ABC2322	ABC0105	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.968
gmk	ndk	ABC2322	ABC1890	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.925
gmk	purB	ABC2322	ABC1026	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.921
gmk	relA	ABC2322	ABC1570	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.930
gmk	rpoZ	ABC2322	ABC2321	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.962
gmk	xpt	ABC2322	ABC1443	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.963
guaA	gmk	ABC0936	ABC2322	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.979
guaA	guaC	ABC0936	ABC3216	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.	0.999
guaA	hprT	ABC0936	ABC0105	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.980
guaA	ndk	ABC0936	ABC1890	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.724
guaA	purB	ABC0936	ABC1026	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.899
guaA	relA	ABC0936	ABC1570	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.	0.532
guaA	xpt	ABC0936	ABC1443	GMP synthetase; Catalyzes the synthesis of GMP from XMP.	Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.	0.989