Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ABC2349Conserved hypothetical protein. (98 aa)    
Predicted Functional Partners:
sigG
DNA-directed RNA polymerase sigma factor sigma-G; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.921
sigE
DNA-directed RNA polymerase sigma-29 factor sigma-E; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.895
spoIIGA
Sporulation sigma-E factor processing peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
 
   
 0.881
ABC2707
Conserved hypothetical protein; Probably functions as a manganese efflux pump.
  
  
 0.827
tepA
Translocation-enhancing protein TepA.
 
   
 0.815
spoIIR
Stage II sporulation protein R.
 
     0.807
ABC1796
Stage V sporulation protein AC.
  
    0.797
spoVAC
Stage V sporulation protein AC.
  
    0.791
spoIIID
Stage III sporulation protein D.
  
  
 0.783
spoIIIAA
Stage III sporulation protein AA.
  
    0.780
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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