Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABC2405Conserved hypothetical protein; Belongs to the UPF0637 family. (211 aa)    
Predicted Functional Partners:
ABC2404
Inositol-1-monophosphatase.
 
     0.727
ABC2403
3-hydroxyisobutyrate dehydrogenase.
       0.561
ABC2141
Conserved hypothetical protein; Belongs to the HesB/IscA family.
  
  
 0.532
mecA-2
Negative regulator of genetic competence MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.
  
     0.498
ABC1728
Conserved hypothetical protein.
 
    0.421
ABC1463
Glucanase.
   
  
 0.418
ABC2381
Conserved hypothetical protein; Belongs to the UPF0342 family.
  
     0.403
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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