STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (361 aa)    
Predicted Functional Partners:
pdhC
Pyruvate dehydrogenase E2 component.
 
 0.999
pdhB
Pyruvate dehydrogenase E1 component beta subunit.
 0.999
pdhD
Pyruvate dehydrogenase E3 component.
 
 
 0.997
bkdA2
Branched-chain alpha-keto acid dehydrogenase E1 component beta chain.
 0.996
acoB
Acetoin dehydrogenase E1 component beta subunit.
 0.995
acoC
Acetoin dehydrogenase E2 component.
 
 0.991
acoL
Acetoin dehydrogenase E3 component.
 
 
 0.988
lpd
Branched-chain alpha-keto acid dehydrogenase E3 component.
 
 
 0.987
pycA
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.944
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.940
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.