STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bcdLeucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (365 aa)    
Predicted Functional Partners:
bkdA1
Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain.
  
 
 0.995
bkdA2
Branched-chain alpha-keto acid dehydrogenase E1 component beta chain.
  
 
 0.994
gltA
Glutamate synthase large subunit.
  
 
 0.978
lpd
Branched-chain alpha-keto acid dehydrogenase E3 component.
  
  
 0.952
bkdB
Branched-chain alpha-keto acid dehydrogenase E2 component.
  
  
 0.951
ABC1931
Branched-chain amino acid aminotransferase.
  
 
 0.918
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
   
 0.915
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.912
pta
Phosphotransacetylase.
  
  
 0.762
bkdR
sigma-L-dependent transcriptional regulator.
 
   
 0.582
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
Server load: low (26%) [HD]