Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABC2525Dithiol-disulfide isomerase; Belongs to the UPF0413 family. (300 aa)    
Predicted Functional Partners:
ABC2524
Conserved hypothetical protein.
  
  
 0.994
spxA
Conserved hypothetical protein; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
  
 
 
 0.868
erzA
Negative regulator of FtsZ ring formation.
  
     0.726
divIC
Cell-division initiation protein.
  
     0.725
ABC2771
Conserved hypothetical protein; Belongs to the UPF0354 family.
  
     0.724
ABC1600
Hypothetical protein.
  
     0.710
ABC2741
Adenine-specific methyltransferase.
  
     0.708
ABC2638
Conserved hypothetical protein.
 
  
 0.700
ABC0880
CAAX amino terminal protease family protease.
 
     0.699
ABC2523
Lytic transglycosylase.
   
   0.689
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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