Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABC2741Adenine-specific methyltransferase. (328 aa)    
Predicted Functional Partners:
erzA
Negative regulator of FtsZ ring formation.
 
     0.780
ABC2526
Competence protein/transcription factor.
  
     0.772
ABC1904
Conserved hypothetical protein.
  
     0.765
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
    0.761
ABC2424
Conserved hypothetical protein; Belongs to the UPF0356 family.
  
     0.746
ABC1088
Conserved hypothetical protein.
  
     0.724
ABC2767
General stress protein.
  
     0.715
ABC2525
Dithiol-disulfide isomerase; Belongs to the UPF0413 family.
  
     0.708
ABC2666
Conserved hypothetical protein.
  
     0.708
ABC2162
Conserved hypothetical protein.
  
     0.706
Your Current Organism:
Bacillus clausii
NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16
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