sppA protein (Bacillus clausii) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

sppA

Signal peptidase SppA. (328 aa)

Predicted Functional Partners:

ABC2746

0.970

secG

0.573

sigW

0.557

rasP

0.552

prsA

0.526

sipW

0.524

sipV

0.523

prsW

0.520

ABC2040

0.497

ABC2745

0.491

Your Current Organism:

Bacillus clausii

NCBI taxonomy Id: 66692
Other names: B. clausii KSM-K16, Bacillus clausii KSM-K16, Bacillus sp. (strain KSM-K16), Bacillus sp. KSM-K16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABC2040	sppA	ABC2040	ABC2747	Conserved hypothetical protein.	Signal peptidase SppA.	0.497
ABC2745	ABC2746	ABC2745	ABC2746	Conserved hypothetical protein.	Conserved hypothetical protein.	0.500
ABC2745	sppA	ABC2745	ABC2747	Conserved hypothetical protein.	Signal peptidase SppA.	0.491
ABC2746	ABC2745	ABC2746	ABC2745	Conserved hypothetical protein.	Conserved hypothetical protein.	0.500
ABC2746	sppA	ABC2746	ABC2747	Conserved hypothetical protein.	Signal peptidase SppA.	0.970
prsA	prsW	ABC1527	ABC1865	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	0.451
prsA	rasP	ABC1527	ABC2235	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	Zn-dependent protease; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	0.662
prsA	secG	ABC1527	ABC3008	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	Preprotein translocase subunit G; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.633
prsA	sipV	ABC1527	ABC1475	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	Signal peptidase I; Belongs to the peptidase S26 family.	0.530
prsA	sipW	ABC1527	ABC0753	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	Signal peptidase I.	0.530
prsA	sppA	ABC1527	ABC2747	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	Signal peptidase SppA.	0.526
prsW	prsA	ABC1865	ABC1527	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	0.451
prsW	rasP	ABC1865	ABC2235	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Zn-dependent protease; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	0.552
prsW	secG	ABC1865	ABC3008	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Preprotein translocase subunit G; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.530
prsW	sigW	ABC1865	ABC0239	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	DNA-directed RNA polymerase ECF-type sigma factor sigma-W; Belongs to the sigma-70 factor family. ECF subfamily.	0.580
prsW	sipV	ABC1865	ABC1475	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Signal peptidase I; Belongs to the peptidase S26 family.	0.460
prsW	sipW	ABC1865	ABC0753	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Signal peptidase I.	0.460
prsW	sppA	ABC1865	ABC2747	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Signal peptidase SppA.	0.520
rasP	prsA	ABC2235	ABC1527	Zn-dependent protease; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Protein export protein PrsA; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.	0.662
rasP	prsW	ABC2235	ABC1865	Zn-dependent protease; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	Conserved hypothetical protein; Involved in the degradation of specific anti-sigma factors. Responsible for Site-1 cleavage of the RsiW anti-sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity).	0.552