| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABC1585 | moeB | ABC1585 | ABC1724 | Iron-sulfur cofactor synthesis. | Molybdopterin biosynthesis protein MoeB. | 0.958 |
| ABC1585 | nifS | ABC1585 | ABC1546 | Iron-sulfur cofactor synthesis. | Cysteine desulfurase. | 0.918 |
| ABC1585 | nifZ | ABC1585 | ABC2750 | Iron-sulfur cofactor synthesis. | Cysteine desulfurase. | 0.922 |
| ABC1585 | thiG | ABC1585 | ABC1735 | Iron-sulfur cofactor synthesis. | Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.567 |
| ABC1585 | thiI | ABC1585 | ABC2749 | Iron-sulfur cofactor synthesis. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.983 |
| ABC1585 | trmU | ABC1585 | ABC1586 | Iron-sulfur cofactor synthesis. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.967 |
| ABC2317 | nifZ | ABC2317 | ABC2750 | RNA-binding protein Sun; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Cysteine desulfurase. | 0.525 |
| ABC2317 | thiI | ABC2317 | ABC2749 | RNA-binding protein Sun; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.808 |
| ABC2317 | tilS | ABC2317 | ABC0104 | RNA-binding protein Sun; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.556 |
| ABC2317 | trmU | ABC2317 | ABC1586 | RNA-binding protein Sun; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.563 |
| ABC3912 | thiI | ABC3912 | ABC2749 | Conserved hypothetical protein; May function as heme-dependent peroxidase. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.626 |
| erzA | nifZ | ABC2751 | ABC2750 | Negative regulator of FtsZ ring formation. | Cysteine desulfurase. | 0.626 |
| erzA | thiI | ABC2751 | ABC2749 | Negative regulator of FtsZ ring formation. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.626 |
| moeB | ABC1585 | ABC1724 | ABC1585 | Molybdopterin biosynthesis protein MoeB. | Iron-sulfur cofactor synthesis. | 0.958 |
| moeB | nifS | ABC1724 | ABC1546 | Molybdopterin biosynthesis protein MoeB. | Cysteine desulfurase. | 0.953 |
| moeB | nifZ | ABC1724 | ABC2750 | Molybdopterin biosynthesis protein MoeB. | Cysteine desulfurase. | 0.951 |
| moeB | thiG | ABC1724 | ABC1735 | Molybdopterin biosynthesis protein MoeB. | Thiamine biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.980 |
| moeB | thiI | ABC1724 | ABC2749 | Molybdopterin biosynthesis protein MoeB. | Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.637 |
| moeB | tilS | ABC1724 | ABC0104 | Molybdopterin biosynthesis protein MoeB. | Cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.475 |
| nifS | ABC1585 | ABC1546 | ABC1585 | Cysteine desulfurase. | Iron-sulfur cofactor synthesis. | 0.918 |
